Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the cure of multiple myeloma. Its synthesis or review is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound within the synthesis of imatinib, a drug that targets unique forms of most cancers, which include Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is very important for optimizing the output approach and making sure superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilised to take Cb 7598 care of breast cancer, and these intermediates are involved with its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the cure of breast cancer. Different intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the cure of colorectal most cancers and little mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is linked to the 4S)-3-Hydroxy-4-phenyl-2-azetidinone synthesis of adamantane derivatives, which have various programs, including antiviral properties.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be used in meals, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor inside the synthesis of canagliflozin, a medication utilised to deal with sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).